Integrated Simulation Biomedical Engineering Laboratory

Creative Flow Research Division

Integrated Simulation Biomedical Engineering Laboratory

Professor
Toshiyuki
Hayase
Associate Professor
Atsushi
Shirai
Assistant Professor
Suguru Miyauchi

Circulatory disease is the second major cause of death in japan next to the cancer, and, therefore, understanding the blood flow is essential to realize a healthy society. Even a state-of-the-art medical equipment is not sufficient to measure the complete information of the blood flow in a invio. The fastest supercomputer may perform a ultra-high speed computation(real-time computation), but is inherently incapable to reproduce the real blood flows due to the lack of the exact computational condition for the relevant flows. Our laboratory is doing a reserch to realize an advanced medical treatment by understanding complex blood flows in living bodies through measurement-integrated simulation which enables us to perform a highly-accurate ultra-high speed computation(super-real-time computation)of the flows.

Integration of Measurement and Simulation in Medical Engineering

Accurate information of real blood flow in a living body is essential for developing advanced diagnosis and treatment. Measurement-integrate(MI)blood flow simulation system is being developed by integrating medical imaging measurement and computational flow simulation based on the observer theory.

Friction Characteristics of Neutrophils on Endothelial Cell Layer

Neutrophils travel through narrow rubbing against endothelial cell layer of the vessels. Since flow characteristics of the neutrophils in the microcirculation is essential for the understanding of immune response of the cells, we have observed friction characteristics of the neutrophils on the endothelial cells using the inclined centrifuge microscope.

Fluis-Structure Interaction Simulation of Blood Flow in the Atrium

Atrial fibrillation increases the risk if thrombus formation, which can cause cerebral infraction. However, the relevance of hemodynamics to the disease is little known. We investigate hemodynamics stresses and vortex formation in the atrium with fluid-structure interaction simulation using a model of a left atrium obtained by MRI.

Integrated Simulation Biomedical Engineering Laboratory