{"id":145,"date":"2021-03-21T16:32:20","date_gmt":"2021-03-21T07:32:20","guid":{"rendered":"http:\/\/www.ifs.tohoku.ac.jp\/eng\/?page_id=145"},"modified":"2026-04-02T11:49:45","modified_gmt":"2026-04-02T02:49:45","slug":"bfdl","status":"publish","type":"page","link":"https:\/\/www.ifs.tohoku.ac.jp\/eng\/research\/dv_lyc\/bfdl\/","title":{"rendered":"Biomedical Flow Dynamics Laboratory"},"content":{"rendered":"<div class=\"research\">\r\n<div class=\"header\">\r\n<div class=\"wrapper\">\r\n<div class=\"clearfix\"><ul class=\"breadcrumb\">\n<li><a href=\"\/jpn\/\">TOP<\/a><\/li>\n<li><a href=\"https:\/\/www.ifs.tohoku.ac.jp\/eng\/research\/\">Research<\/a><\/li>\n<li><a href=\"https:\/\/www.ifs.tohoku.ac.jp\/eng\/research\/dv_lyc\/\">Lyon Center(LyC)<\/a><\/li>\n<li>Biomedical Flow Dynamics Laboratory<li>\n<\/ul><\/div>\r\n<h2>Lyon Center(LyC) &#8211; Integration Research Center for Materials and Fluid Sciences<\/h2>\r\n<h3>Biomedical Flow Dynamics Laboratory<\/h3>\r\n<div class=\"clearfix\">\r\n<ul class=\"professor\">\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/professor\/makotoohta.jpeg\" \/>\r\n<p><span>Professor<\/span>Makoto Ohta<\/p>\r\n<\/li>\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/professor\/kosukegawa.jpg\" \/>\r\n<p><span>Specially Appointed Associate Professor<\/span>Hiroyuki Kosukega<br \/>wa<\/p>\r\n<\/li>\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/professor\/anzaihitomi_v2.jpg\" \/>\r\n<p><span>Associate Professor<\/span>Hitomi Anzai<\/p>\r\n<\/li>\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/professor\/LiaoJing.jpg\" \/>\r\n<p><span>Specially Appointed Assistant Professor<\/span>Jing LIAO<\/p>\r\n<\/li>\r\n<\/ul>\r\n<\/div>\r\n<div class=\"clearfix\">\r\n<ul class=\"sdgs\">\r\n<li style=\"list-style-type: none;\">\r\n<ul class=\"sdgs\">\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/sdgs_icon_e\/sdgs-03.jpg\" \/><\/li>\r\n<\/ul>\r\n<\/li>\r\n<\/ul>\r\n<\/div>\r\n<div class=\"clearfix\">\r\n<div class=\"labo\"><a href=\"http:\/\/www.ifs.tohoku.ac.jp\/bfc\/\" target=\"_blnak\" rel=\"noopener\">Enter the Lab Page<\/a><\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<div class=\"gray\">\r\n<div class=\"wrapper\">The focus of the Biomedical Flow Dynamics Laboratory is to develop new concept of implant especially based on flow and to establish new methods for evaluating the implants. For example, medical doctors use medical devices for an endovascular treatment of intracranial aneurysm. The purpose of this medical device is to control blood flow. However, only development is not enough to reach patients. The establishment of evaluation system with safety and objective manner should be necessary. And the training system for the device is also necessary. We try to find out the flow around the medical device or in human organs using CFD (computational fluid dynamics), AI, PIV or ultrasound for velocity distribution using bio-model. The findings could relate to the mechanism of disease or prediction of blood flow. These research activities are performed with medical doctors, medical companies and a venture business company called Blue-Practice.<\/div>\r\n<\/div>\r\n<div class=\"contents\">\r\n<div class=\"wrapper\">\r\n<h4>Development of PVA-H 3D printer<\/h4>\r\n<div>PVA-H has an advantage of mechanically mimicking human organs. We developed a new 3D printer for specific patient shape made of PVA-H. If medical doctors receive a model with the patient specific shape, they can check their procedure of treatment before the real treatment. The figure shows the concept of PVA-H 3D printer and a model.<\/div>\r\n<div class=\"photo\">\r\n<div class=\"clearfix\">\r\n<ul class=\"multi\">\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/division\/04_img\/4_001-2.png\" \/><\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<div class=\"clearfix\">\r\n<ul class=\"sdgs\">\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/sdgs_icon_e\/sdgs-03.jpg\" \/><\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<div class=\"contents\">\r\n<div class=\"wrapper\">\r\n<h4>Visualization of flow in model<\/h4>\r\n<div>Once a new device is developed physically such as catheter or stent, the developer needs to check the efficiency using a real model system. We developed system with the PVA-H realistic model to visualize the flow around the medical device.<\/div>\r\n<div class=\"photo\">\r\n<div class=\"clearfix\">\r\n<ul class=\"multi\">\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/division\/04_img\/4_003.jpg\" \/><\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<div class=\"clearfix\">\r\n<ul class=\"sdgs\">\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/sdgs_icon_e\/sdgs-03.jpg\" \/><\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<div class=\"contents\">\r\n<div class=\"wrapper\">\r\n<h4>Hemodynamic analysis using CFD<\/h4>\r\n<div>Blood flow is thought to have a strong relation to the initiation\/growing of disease. Computational simulation could realize the blood flow. And the simulation technology can offer an optimal treatment method. The figure shows the computational fluid dynamics (CFD) for a disease with several outlets. We are now developing the methodology of the simulation.<\/div>\r\n<div class=\"photo\">\r\n<div class=\"clearfix\">\r\n<ul class=\"multi\">\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/division\/04_img\/4_004.jpg\" \/><\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<div class=\"clearfix\">\r\n<ul class=\"sdgs\">\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/sdgs_icon_e\/sdgs-03.jpg\" \/><\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<div class=\"contents\">\r\n<div class=\"wrapper\">\r\n<h4>Development of standard cerebral artery coordinate<\/h4>\r\n<div>Generally, &#8220;disease&#8221; means &#8220;not health&#8221; state, but what is the definition of \u201chealthy&#8221;? Cerebrovascular disease often changes the vessel morphology. Then, the question is how to set the threshold of disease on morphological changes. To develope the standard and variety of cerebrovascular structure, we construct &#8220;averaged geometry&#8221; of blood vessels obtained from magnetic resonance imaging (MRI).<\/div>\r\n<div class=\"photo\">\r\n<div class=\"clearfix\">\r\n<ul class=\"multi\">\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/division\/04_img\/4_005.jpg\" \/>\u69cb\u7bc9\u3055\u308c\u305f\u6a19\u6e96\u8133\u8840\u7ba1\u5ea7\u6a19\u7cfb<\/li>\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/division\/04_img\/4_006.png\" \/>\u6a19\u6e96\u8133\u8840\u7ba1\u5ea7\u6a19\u7cfb\u3068\u60a3\u8005\u56fa\u6709\u4e2d\u5fc3\u7dda\u306e\u9055\u3044<\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<div class=\"clearfix\">\r\n<ul class=\"sdgs\">\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/sdgs_icon_e\/sdgs-03.jpg\" \/><\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<div class=\"contents\">\r\n<div class=\"wrapper\">\r\n<h4>Prediction of 3D hemodynamics by deep learning technique<\/h4>\r\n<div>Hemodynamics measurement and computational fluid dynamics (CFD) have been performed under invasive\/non-invasive techniques. However, still it is challenging to obtain detailed flow field within a second by measurement nor CFD. Then, we developed deep learning technique to predict 3D hemodynamics on cardiovascular system. This deep learning network can allow to obtain CFD-like results within a second, which needs 10 min in conventional CFD.<\/div>\r\n<div class=\"photo\">\r\n<div class=\"clearfix\">\r\n<ul class=\"multi\">\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/division\/04_img\/4_007.jpg\" \/>\u5927\u52d5\u8108\u6d41\u308c\u306e\u6d41\u7dda\u3092\u53ef\u8996\u5316\uff08\u5de6\uff1aCFD\u306b\u3088\u308a\u5f97\u3089\u308c\u308b\u6570\u5024\u89e3\u6790\u7d50\u679c\u3001\u53f3\uff1a\u30c7\u30a3\u30fc\u30d7\u30e9\u30fc\u30cb\u30f3\u30b0\u306b\u3088\u308b\u4e88\u6e2c\u7d50\u679c\uff09<\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<div class=\"clearfix\">\r\n<ul class=\"sdgs\">\r\n<li><img decoding=\"async\" src=\"\/jpn\/wp-content\/themes\/ifs\/images\/research\/sdgs_icon_e\/sdgs-03.jpg\" \/><\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<div class=\"footer clearfix\">\r\n<div class=\"wrapper\">\r\n<div class=\"labo\"><a href=\"http:\/\/www.ifs.tohoku.ac.jp\/bfc\/\" target=\"_blnak\" rel=\"noopener\">Enter the Lab Page<\/a><\/div>\r\n<\/div>\r\n<\/div>\r\n<div class=\"news-list clearfix\">\n<div class=\"wrapper\">\n<div class=\"tag\"><a href=\"https:\/\/www.ifs.tohoku.ac.jp\/eng\/news\/tag\/crfrd_bfdl\/\">\uff03Biomedical Flow Dynamics Laboratory<\/a><\/div>\n<\/div>\n<div class=\"slide-wrapper\">\n<div class=\"slide-index\">\n<div class=\"swiper-container\">\n<ul class=\"swiper-wrapper clearfix\">\n<li class=\"swiper-slide\"><a href=\"https:\/\/www.ifs.tohoku.ac.jp\/eng\/news\/2460\/\"><img loading=\"lazy\" decoding=\"async\" width=\"671\" height=\"421\" src=\"https:\/\/www.ifs.tohoku.ac.jp\/eng\/wp-content\/uploads\/sites\/3\/2026\/10\/TheRomanceofReserch_anzai.jpg\" class=\"attachment-post-thumbnail size-post-thumbnail wp-post-image\" alt=\"\" \/>Interview with Associate Professor Hitomi Anzai Featured in Tohoku University&#8217;s &#8220;The Romance of Research&#8221;<\/a><\/li>\n<\/ul>\n<\/div>\n<div class=\"swiper-button-prev\"><\/div>\n<div class=\"swiper-button-next\"><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Lyon Center(LyC) &#8211; Integration Research Center for Materials and Fluid Sciences Biomedical Flow Dynamics Laboratory ProfessorMakoto Ohta Specially Appointed Associate ProfessorHiroyuki Kosukegawa Associate ProfessorHitomi Anzai Specially Appointed Assistant ProfessorJing LIAO Enter the Lab Page The focus of the Biomedical Flow Dynamics Laboratory is to develop new concept of implant especially based on flow and to [&hellip;]","protected":false},"author":1,"featured_media":0,"parent":237,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-145","page","type-page","status-publish","hentry"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.1.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"An interview with Associate Professor Hitomi Anzai of the Institute of Fluid Science has been featured in &quot;The Romance of Research,&quot; a special website highlighting researchers at Tohoku University.The article explores her research, ranging from computer simulations of blood flow to AI-based modeling and the use of &quot;virtual patients&quot; in medical device development. She also\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.ifs.tohoku.ac.jp\/eng\/news\/2460\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 5.0.1.1\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Institute of Fluid Science, Tohoku University -\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"An article featuring Associate Professor Hitomi Anzai (Biomedical Flow Dynamics Laboratory) has been published on Tohoku University\u2019s researcher profile page, \u201cThe Romance of Research.\u201d\" \/>\n\t\t<meta property=\"og:description\" content=\"An interview with Associate Professor Hitomi Anzai of the Institute of Fluid Science has been featured in &quot;The Romance of Research,&quot; a special website highlighting researchers at Tohoku University.The article explores her research, ranging from computer simulations of blood flow to AI-based modeling and the use of &quot;virtual patients&quot; in medical device development. 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